Grove Lab Team
Joe Grove
Principal Investigator
Expertise: Experimental virology, computational structural biology, making coffee
Investigating: What AI structure prediction can do for virology
Diego Cantoni
Postdoctoral Investigator
Expertise: Viral glycoproteins and virus entry (resident musician and Tiramisu expert)
Investigating: Characterising coronavirus and filovirus glycoproteins using a mixture of dry and wet lab techniques.
Bridget Larman
Postdoctoral Investigator
Expertise: Experimental virology and protein biology (resident baked-good eater and bibliophile)
Investigating: Characterising how AI designed proteins bind to HCV glycoproteins to block infection, and evaluating different AI programs for designing binders. Exploring how we can develop these techniques to apply them to other viruses.
Sarah Little
Research Technician
Expertise: Infection biology and neuroscience (resident baker and wildlife photographer)
Investigating: Using AI designed binders to block virus entry, currently in HCV and expanding to more viruses. Also investigating interactions between SARS-CoV-2 and the ACE2 receptor, and how changes in the receptor binding motif influence this.
Stephen Devlin
PhD Student
Expertise: Experimental virology, bioinformatics (and secret mycologist)
Investigating: Hepatitis C Virus
Charlotte Lewis
PhD Student
Expertise: Experimental virology, structural biology and protein design
Investigating: Caliciviruses (co-supervised by David Bhella and Margaret Hosie)
Ross King
PhD Student
Expertise: Computational virology
Investigating: Flaviviruses (co-supervised by Kevin Maringer, Pirbright Institute)
Alumni
Michael Oliver
Postdoctoral Investigator
Expertise: Protein biology and structural biology
Investigated: Hepatitis C Virus and AlphaFold-ology